By Meghan Overdeep
Updated Jul 28, 2016 @ 10:15 am
Credit: Kevin Mazur/WireImage

After decades of friendship and three romantic comedies, a new chapter in Meg Ryan and Tom Hanks's relationship is upon us. We never thought we'd see the day, but nearly 20 years after the debut of You've Got Mail, Ryan and Hanks have reunited yet again (although just briefly) on the big screen.

Hanks plays Ryan's deceased husband in Ithaca, Ryan's upcoming film, and directorial debut.

Ithaca, which was adapted from William Saroyan's 1943 novel The Human Comedy, tells the story of a teenager named Homer (played by Alex Neustaedter), who works as a telegraph messenger to support his recently widowed mother (Ryan) his older brother (played by Jack Quaid, Ryan's real-life son), is shipped off to fight in World War II.

Ryan told Entertainment Weekly that Hanks's scene in the film took just one day to shoot—a day he was happy to give to his longtime friend.

"He's just so dear. He so did not have to do that," Ryan said. "At the end of his time, he says to the crew, 'All right, gather 'round. Listen, I know we've gotten to know each other very well over the last 10 hours together, but I just want to thank you for being here for my friend Meg.'"

Watch the first official trailer for Ithaca above. The movie is set for a limited release on Sept. 9.