By Selene Milano
Updated Nov 17, 2011 @ 2:00 pm
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Credit: WireImage; NBC/Globe

George Clooney’s new movie The Descendants opened yesterday, and it's already generating lots of major Oscar buzz. To celebrate the heartthrob’s latest success story, let’s look back at his transformation from silver screen Facts of Life star to internationally-loved celebrity. See his evolution in the gallery now.