Christina Applegate Fights, Runs, and Walks to Rid the World of Cancer

Not sure how to celebrate Mother’s Day this year? Try taking a walk for a cause this weekend. We caught up with actress Christina Applegate, who through her own organization, Right Action for Women, champions the fight against women’s cancer. Applegate is co-hosting the 21st Annual EIF Revlon Run/Walk for Women, which takes place May 10 at the Los Angeles Memorial Coliseum.

So, why walk? "You will never have a more inspiring three miles of your life," says Applegate. "One of the most incredible things you can do is walk with these women and these men and these children who have all been affected by cancer. Because you know what? We are all affected by it. One in eight women is going to get breast cancer in their lifetime. One in 36 will die from it." Applegate, whose mother battled cancer twice, and was personally diagnosed with breast cancer in 2008, has made it her mission to fight this disease for all women and advocates prevention and early detection. "We need to get rid of this thing. We’ve got to raise money and get rid of it! Wouldn’t it be nice to just live in a world where we don't have to fear this?"

Bring along your mom, daughter, sister, or husband, and wear good walking shoes and a hat to join Applegate and co-hosts Halle Berry and Bruce Willis as they Run/Walk to help raise money to support cancer research. Early registration is encouraged and can be done by visiting revlonrunwalk.org (or by calling the event hotline at 855-434-3779). Registration is also available on site, the day of the event.

Can’t make it to the walk? You can still give to the cause. Designer Alex Woo created a sterling silver tree of life necklace with proceeds going to Applegate's charity, Right Action for Women ($198; alexwoo.com).

Need more ideas for mom on Mother's Day? Take a look at our gift guide for the special day!

—Karen Levy