Betty White
Credit: Vincent Sandoval/Getty Images

Betty White truly is America’s sweetheart. At 94-years-old, White’s illustrious career is still booming, and she's all set to appear on NBC’s new show, Crowded, after her five-year run on Hot in Cleveland ended in June. The comedienne also fronted three seasons of the hidden-camera show, Betty White’s Off Their Rockers, where senior citizens pulled pranks on unsuspecting victims.

The star is best known for her roles in the sitcoms Mary Tyler Moore and The Golden Girls, and she rose back into the spotlight when she played Ryan Reynolds's mischievous grandma in the 2009 film, The Proposal. Since then, her career has skyrocketed, with Super Bowl commercials and TV appearances turning the hilarious actress into a viral sensation. Her 2015 People’s Choice Award for Favorite TV Icon is the perfect example of her widespread fandom.

Here’s a look back at her funniest late-night TV moments in honor of her special day.

When she played a nagging Eve alongside Johnny Carson’s Adam:

When she posed as a John McCain speechwriter and called Sarah Palin a "crazy b*tch":

When she had hilariously confusing answers to census taker Tina Fey's questions:

When she told Craig Ferguson she was running for president because she "needed some cash":

When her top 10 tips for living a long and healthy life included "try not to die":

When she changed her age from 90 to 45 on Conan:

When she asked a fan who had a tattoo of her face, "You have to live with that all the time?"

When she prank called James Corden and was a totally convincing diva:

Happy birthday, Betty!