Load on the moisturizers. “Creams and washes with basic hydrators like glycerin, ceramides, and cholesterol can actually plump furrows and grooves,” says N.Y.C. dermatologist Frederic Brandt. Older cells are even more vulnerable to damaging UV rays, so diligent sunscreen use is an absolute must. At night, break out the big guns: A vitamin A–based retinol speeds cell turnover and improves skin rejuvenation.