You may not want to smother a zit with makeup, but hydrocortisone? "Go for it!" says Dr. Sherber. Before bed, slather on the anti-inflammatory cream, then seal it in with a waterproof bandage. "This intensifies the potency, so the next morning the pimple will be smaller and less red. It's nearly as effective as getting a steroid injection."
Nexcare Waterproof Bandages, $4/20; at drugstores.Read MoreLess